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University of Saskatchewan, Department of Computer Science


2002-2003 Seminar Series

4D Bioinformatics

Christoph W. Sensen
University of Calgary
Sun Center of Excellence for Visual Genomics
Calgary, Alberta

DEPARTMENT SEMINAR
DATE: Friday, September 27, 2002
TIME: 10:30 a.m.
PLACE: Arts 134
*** Everyone is welcome ***
NOTE: SPECIAL TIME AND PLACE

Abstract

The genomic data space is growing increasingly complex. The information about completely sequenced genomes is growing exponentially. In addition, the number of data types recorded (genomic sequence, proteomic information, gene expression studies) is also increasing rapidly.

While the initial genomic data types lend themselves to be represented along two-dimensional (linear) models of the molecules (DNA sequences and proteins), the proteomic and gene expression data can only be fully understood using spatial (3D) and temporal representations.

To address the new needs in bioinformatics, we have established a new research facility, which features the first Java-3D enabled CAVE automated virtual environment. This facility is used to build models of cells, tissues and entire organisms, including the human body using advanced imaging data. The imaging information is then combined with genomic data to reconstruct gene expression patterns, protein modifications and other large-scale experiments in four dimensions.

About the speaker

Christoph received the Ph.D. degree from Cologne, Germany and is currently a Professor in the Department of Biochemistry & Molecular Biology at the University of Calgary. Dr. Sensen's laboratory has been involved in Genomics and Bioinformatics for more than seven years. Our past work has focused on the generation of complete genomic sequences (e.g. the Sulfolobus solfataricus P2 genome project) and the analysis of genomic information.

Recently the lab has expanded into researching XML-Java applications, which will allow complex queries of genomic datasets and a much more sophisticated viewing environment. [an error occurred while processing this directive]